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Lutoral-E 2 MG/80 MCG 20 tabs, Chlormadinone, Mestranol

Lutoral-E  2 MG/80 MCG  20 tabs, Chlormadinone, Mestranol
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Lutoral-E  2 MG/80 MCG  20 tabs, Chlormadinone, Mestranol


INDICATIONS mestranol and chlormadinone acetate are indicated in the treatment of menstrual disorders (amenorrhea, polymenorrhea, oligomenorrhea, opsomenorrea, proimenorrea, menorrhagia, hypomenorrhea), dysmenorrhea, endometriosis and dysfunctional uterine bleeding.

Chlormadinone acetate is a progestogen very effective, 35 times more effective than oral norethindrone, and 60 times as effective as progesterone subcutaneously.

CONTRAINDICATIONS: Chlormadinone not be used when there is any of the following conditions: pregnancy, lupus erythematosus, thrombophlebitis, thromboembolic disease or a history, or a history of these worsening disease, cerebrovascular disease, ischemic heart disease or history thereof, or abnormal functioning liver disease , liver tumors, history of jaundice cholestatic jaundice of pregnancy or oral contraceptive use, breast cancer or cancer of the genital organs, undiagnosed abnormal vaginal bleeding, hypersensitivity to chlormadinone acetate or other ingredients.

PRECAUTIONS: Caution should be exercised when administering chlormadinone acetate and mestranol patients with alterations in lipid metabolism, changes in the incidence or pattern of headaches, emotional disorders, which could exacerbate uterine leiomyoma, bladder disease, uremic syndrome hemolytic, increased blood pressure, liver tumors including hepatocellular carcinoma, vascular disease risk related to dose, thromboembolism, risk of visual disturbances, loss of vision, retinal thrombosis, papilledema, proptosis and diplopia. Curve decreases glucose tolerance.

RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION: Not to be used as a diagnostic test for pregnancy. It is present in breast milk. Its use during the early stages of pregnancy and lactation are restricted, the effect on the child may have is unknown.

There may be dizziness, nausea, vomiting and gastrointestinal symptoms such as abdominal pain, headache, nervousness, anxiety, mainly due to estrogen.

DRUG INTERACTIONS AND OTHER GENDER: mestranol and chlormadinone acetate may alter the effectiveness of other medications such as anticonvulsants, antihypertensive agents (eg, guanethidine), beta blockers, barbiturates, ampicillin, griseofulvin, hypoglycemic agents, oral anticoagulants, theophylline , tranquilizers, tricyclic antidepressants, vitamins and anti-epileptics.

DOSAGE AND ADMINISTRATION: In all disorders metropathy menstrual bleeding except in the recommended dose of chlormadinone acetate and mestranol is: one tablet daily from 5th to 24th day of the cycle for 3 cycles. If necessary, the doctor will determine if given more cycles. If for some reason there forget to take a tablet, it must be administered within 24 hours of the next day.

In metropathy hemorrhagic dose should be: One tablet chlormadinone acetate and mestranol every 6 hours until hemostasis, continue with one tablet daily for 20 days. Subsequently, three cycles of treatment start administering one tablet daily from 5 to 24th days of the cycle.

For the postponement of menstruation the recommended dose is three tablets a day for a week prior to the expected date of the rule, by the time you want to postpone it.

In the case of endometriosis is recommended: Three tablets mestranol and chlormadinone acetate per day (1 every 8 hours) continuously for 6 months. If transhormonal bleeding, the dose should be increased.

PRESENTATION: Box of 20 tablets.

RECOMMENDED STORAGE: Store at room temperature not more than 30 ° C and dry.

Protect from light.
Drug Name: LUTORAL-E
Comparable drug patent: LUTORAL-E
Active substance: chlormadinone / mestranol
Presentation: Tablets
Concentration: 2 MG / 80 MCG
Extended-release tablets: No
Laboratory: PFIZER
Box of 20 Tablets
Made In: Mexico

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